Starting a new school year, Squish, a meek amoeba who loves the comic book exploits of his favorite hero, "Super Amoeba," is determined to get picked for kickball and hang out with the cool kids.

At swim camp, Squish's new friend Basil helps him avoid learning to swim with pranks that sometimes go too far, but the comic book exploits of Squish's idol, "Super Amoeba, " help him deal with Basil and conquer his fear.

Afraid to watch horror movies with his friend, Pod, Squish the amoeba feels better after learning that even comic book superheroes get scared sometimes.