With the Pride gone, every bad guy in the Marvel Universe is trying to fill the void they left behind. The Runaways are the only heroes who can stop them. And what team of young heroes is looking for the Runaways and why?
The kids start running in a different direction. The Runaways take off for the Big Apple. While there, they make surprising allies and even more surprising enemies with a journey through time. Plus, what happens when the teens meet...the Punisher!?